{"id":6075,"date":"2023-03-02T14:30:29","date_gmt":"2023-03-02T13:30:29","guid":{"rendered":"https:\/\/www.hartwigmedicalfoundation.nl\/?post_type=datarequests&#038;p=6075"},"modified":"2023-03-02T14:38:01","modified_gmt":"2023-03-02T13:38:01","slug":"dr-318-the-causes-and-consequences-of-structural-variations-in-cancer","status":"publish","type":"datarequests","link":"https:\/\/www.hartwigmedicalfoundation.nl\/en\/datarequests\/dr-318-the-causes-and-consequences-of-structural-variations-in-cancer\/","title":{"rendered":"DR-318 The causes and consequences of structural variations in cancer"},"content":{"rendered":"<p>Structural variations (SVs) are large scale changes of DNA, which include deletions, duplications, inversion, translocations and other more complex forms. We aim to study the causes of somatic SVs in cancer and elucidate how they contribute to tumor initiation, progression and metastasis. We will develop novel methods to analyze the genomic and transcriptomic sequencing data. We expect to discover new genetic factors and genes contribute to the disease and improve disease prevention and treatment.<\/p>\n<p>Lixing Yang, University of Chicago, USA<\/p>\n","protected":false},"author":3,"featured_media":0,"template":"","request_years":[111],"class_list":["post-6075","datarequests","type-datarequests","status-publish","hentry","request_years-111"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>DR-318 The causes and consequences of structural variations in cancer - Hartwig Medical Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hartwigmedicalfoundation.nl\/en\/datarequests\/dr-318-the-causes-and-consequences-of-structural-variations-in-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DR-318 The causes and consequences of structural variations in cancer - Hartwig Medical Foundation\" \/>\n<meta property=\"og:description\" content=\"Structural variations (SVs) are large scale changes of DNA, which include deletions, duplications, inversion, translocations and other more complex forms. &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.hartwigmedicalfoundation.nl\/en\/datarequests\/dr-318-the-causes-and-consequences-of-structural-variations-in-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Hartwig Medical Foundation\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-02T13:38:01+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.hartwigmedicalfoundation.nl\\\/en\\\/datarequests\\\/dr-318-the-causes-and-consequences-of-structural-variations-in-cancer\\\/\",\"url\":\"https:\\\/\\\/www.hartwigmedicalfoundation.nl\\\/en\\\/datarequests\\\/dr-318-the-causes-and-consequences-of-structural-variations-in-cancer\\\/\",\"name\":\"DR-318 The causes and consequences of structural variations in cancer - 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