DR-259 Role of DNA Damage Tolerance Pathways in Genome Maintenance: Linking Mutations to the Lack of DDT
DNA damage response (DDR) network is critical in maintaining genome integrity. The contribution of the DNA damage tolerance (DDT) system in this network is poorly defined. In this project we strive to delinate mutational profiles to specific defects in the DRR/DDT system.
Heinz Jacobs, Netherlands Cancer Institute, the Netherlands
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