DR-519 Deciphering the molecular landscape of sarcomas

Sarcomas are rare cancers that are difficult to diagnose and treat due to highly variable genetic profiles. This project uses whole‑genome sequencing, transcriptomics, and methylation profiling to map the molecular changes that define different sarcoma types. By analyzing both newly collected and historical tumor samples, we aim to identify biomarkers that improve diagnostic accuracy and reveal vulnerabilities that could guide targeted therapies. The results will help ensure that patients receive more precise diagnoses and better‑matched treatments.

Felix Haglund de Flon, Karolinska Instutet, Sweden