DR-353  Landscape of mutational signatures in appendiceal cancer

Appendiceal cancer is still a poorly understood entity. There are many subtypes and treatment decisions are often made based on guidelines from similar tumors such as colorectal or neuroendocrine tumors. We aim to perform a mutational signatures analysis on existing whole genome sequencing data of appendiceal tumors to try to determine the underlying biological process that is involved in the development of these tumors. We also want to determine if there are subtypes that respond better to chemotherapy than others and therefore optimize patient care.

Marc Attiyeh, Cedars-Sinai Medical Center, USA