DR-446 Fungal Contribution in Metastatic Cancer and Multi-Drug Treatment

This project explores the impact of fungi on cancer progression and treatment response. By examining fungal data from WGS and RNA sequences in cancer samples, alongside clinical annotations about disease and treatment effects, we aim to uncover how fungi might influence tumor spread and resistance to multiple drugs. Our techniques include aligning fungal sequences to identify relevant species and assessing their relationships with cancer characteristics and immune responses. The findings could offer new insights into personalized cancer therapy, potentially leading to more effective treatments by considering fungal interactions within the tumor environment.

Iliyan Iliev, Weill Cornell Medicine, United States of America