DR-079 Technology Assessment of Next Generation Sequencing in Personalized Oncology (TANGO)
The introduction of new therapeutic options, i.e. antiangiogenic drugs and immunotherapy, has significantly changed the treatment and perspectives of patients with advanced and metastatic renal cell cancer (RCC). Currently, the choice for first-line treatment is based on a risk calculation model, using only clinical parameters such as performance status. The aim of the current project is to describe the genomic landscape of RCC patients focusing on the immunogenic and angiogenic mutations/genes. More insight into immunogenic and angiogenic driver mutations together with the genomic landscape of RCC may contribute to improved and more individualized therapeutic decision making.
Astrid van der Veldt Erasmus MC the Netherlands
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Zolang de behandelaar niet weet waar de primaire tumor zit, heeft hij ook geen gerichte behandelmogelijkheid en kan ook geen inschatting worden gegeven hoe lang iemand nog heeft.