DR-142 Genomic landscape of non-small cell lung cancer (NSCLC) tumors and metastases.

Despite the advancements in lung cancer treatment in the last decades, most patients diagnosed with non-small cell lung cancer (NSCLC), still suffer from a severe disease characterized by rapid progression and low survival rates. All cancers are caused by genetic alterations in healthy cells. Lung cancer is characterized by a high number of these genetic alterations. We would like to explore the genetic abnormalities that can be found in lung tumors. These abnormalities can help us predict which patients are likely to respond to different therapies. Furthermore, the analysis can probably lead to the discovery of new targets for patient specific therapy.

Joachim Aerts Erasmus MC The Netherlands