DR-145 Immune and stromal gene expression signature in metastatic prostate and breast cancer

The main reason that cancer is lethal lies in its ability to spread in the body, a process called metastasis. The immune system is important in determining tumour development and treatment response. We will conduct in-depth analyses of metastatic cancer by using the transcriptomic data to understand how immune and stromal cell gene expression may be correlated with changes in tumour size and patient outcomes. We will also determine the key genes that the alteration of which may improve disease outcome, which may provide potential therapeutic targets.

Binzhi Qian The University of Edinburgh, QMRI United Kingdom