DR-196 Clinical and Genomic landscape of Carcinoma of Unknown Primary in the Netherlands, compared to metastasised known primary tumours

Patients with carcinoma of unknown primary (CUP) are patients with proven metastases but no primary tumour found. These patients have a very poor prognosis of only 2-3 months median survival.                                                                                                                                                                       

Until now only little research on this patient population is performed in the Netherlands. By improving our knowledge of this entity and comparing it to metastasised known primaries, we hope to improve our current insights.               

Ultimately this will lead to identifying those patients who could benefit from currently available therapies and improve the survival of these treated patients. Moreover, preventing unnecessary treatment will improve the quality of life of those who will not benefit from anticancer therapy.

Yes van de Wouw, Viecuri Medisch Centrum, the Netherlands