DR-381 CHEMOTRANSPORT: exploring influx mediated susceptibility to chemotherapy

To become effective within a tumor cell, chemotherapy needs to be transported into that cell via influx transporters. The activity of these transporters differs between cancer types. The aim of this project is to study whether the activity of these influx transporters can be used to determine cancer susceptibility to chemotherapy. Positive results from this project will be used personalize cancer treatment by allocationg the best chemotherapy to cancers with active drug influx transporters.

Sander Bins, Erasmus MC, the Netherlands