DR-221 Multi-omics profiling of tumors

Cancer is caused by mutations in the DNA, which can be analyzed by sequencing the tumor’s DNA. We can observe the effect mutations have on various levels, including changes in the amount of protein each gene produces. As proteins perform all the cell’s activities, altered levels could affect the function of our cells. To get a more complete insight into processes causing mutations and their consequences, we will look at the DNA and protein level. This will contribute to a more personalized treatment and help, for example, predict the primary location for those metastatic tumors for which this is unknown.

Ivo Gut Centro Nacional de Análisis Genómico (CNAG-CRG) Spain