Personalized selection of experimental treatment in patients with advanced solid cancer is feasible using Whole Genome Sequencing

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Personalized selection of experimental treatment in patients with advanced solid cancer is feasible using Whole Genome Sequencing

04-08-2022

M.A. Pruis, F.H. Groenendijk, K.S. Badloe, A. van Puffelen, D. Robbrecht, W.N.M. Dinjens, S. Sleijfer, A.C. Dingemans, J.H. von der …

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The genomic and transcriptomic landscape of advanced renal cell cancer to individualize treatment strategies

04-08-2022

K. de Joode, W.S. van de Geer, G.J.L.H. van Leenders, P. Hamberg, H.M. Westgeest, A. Beeker, S.F. Oosting, J.M. van …

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Substitution mutational signatures in whole-genome–sequenced cancers in the UK population

04-08-2022

Andrea Degasperi, Xueqing Zou, Tauanne Dias Amarante, Andrea Martinez-Martinez, Gene Ching Chiek Koh, João M. L. Dias, Laura Heskin, Lucia …

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Genome-wide analysis of somatic noncoding mutation patterns in cancer

04-08-2022

Felix Dietlein, Alex B. Wang, Fagre, Anran Tang, Nicolle J. M. Besselink, Cuppen, Chunliang Li, R. Sunyaev, T. Neal, Eliezer …

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Unscrambling cancer genomes via integrated analysis of structural variation and copy number

04-08-2022

Charles Shale, Daniel L. Cameron, Jonathan Baber, Marie Wong, Mark J. Cowley, Anthony T. Papenfuss, Edwin Cuppen, Peter Priestley Cell …

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Distinct Genomic Profiles Are Associated with Treatment Response and Survival in Ovarian Cancer

04-08-2022

Chris J. de Witte, Joachim Kutzera, Arne van Hoeck, Luan Nguyen, Ingrid A. Boere, Mathilde Jalving, Petronella B. Ottevanger, Christa …

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Genome-wide aneuploidy detected by mFast-SeqS in circulating cell-free DNA is associated with poor response to pembrolizumab in patients with advanced urothelial cancer

04-08-2022

Pauline A J Mendelaar, Debbie Robbrecht, Maud Rijnders, Ronald de Wit, Vanja de Weerd, Teoman Deger, Hans M Westgeest, Maureen …

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Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma

04-08-2022

J. Alberto Nakauma-Gonzáleza, Maud Rijnders, Job van Riet, Michiel S.van der Heijden, Jens Voortman, EdwinCuppen, Niven Mehra, Sandra van Wilpe, …

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Genomics – Guided Treatment of Rare Cancer Patients in DRUP

04-08-2022

L.R. Hoes, J.M. van Berge Henegouwen, H. van der Wijngaart, L.J. Zeverijn, D.L. van der Velden, J. van de Haar, …

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Clinical impact of prospective whole genome sequencing in sarcoma patients

04-08-2022

L.J. Schipper, K. Monkhorst, K.G. Samsom, L.J.W. Bosch, P. Snaebjornsson, H. van Boven, P. Roepman, L.E. van der Kolk, W.J. …

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Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features

04-08-2022

Luan Nguyen, Arne Van Hoeck & Edwin Cuppen Nature Communications, July 11, 2022 PMID: 35817764

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Feasibility of whole genome sequencing based tumor diagnostics in routine pathology practice

04-08-2022

Kris G. Samsom, Luuk J. Schipper, Paul Roepman, Linda J.W. Bosch, Ferry Lalezari, Elisabeth G. Klompenhouwer, Adrianus J. de Langen, …

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