Delivering precision oncology to patients with cancer
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Delivering precision oncology to patients with cancer
Joaquin Mateo, Lotte Steuten, Philippe Aftimos, Fabrice André, Mark Davies, Elena Garralda, Jan Geissler, Don Husereau, Iciar Martinez-Lopez, Nicola Normanno, …
Validation of HER2 Status in Whole Genome Sequencing Data of Breast Cancers with the Ploidy-Corrected Copy Number Approach
Marzena Wojtaszewska, Rafał Stępień, Alicja Woźna, Maciej Piernik, Pawel Sztromwasser, Maciej Dąbrowski, Michał Gniot, Sławomir Szymański, Maciej Socha, Piotr Kasprzak, …
Trastuzumab and pertuzumab combination therapy for advanced pre-treated HER2 exon 20-mutated non-small cell lung cancer
J.M. Van Berge Henegouwen, M. Jebbink, L.R. Hoes, H. Van Der Wijngaart, L.J. Zeverijn, D.L. Van Der Velden, P. Roepman, …
Temporal Dissection of Altered Pathways during the Evolution of Cancer
Johanne Ahrenfeldt, Ditte S. Christensen, Mateo Sokač, Judit Kisistók, Nicholas McGranahan, Nicolai J. Birkbak NA, 2022, DOI: 10.20944/preprints202210.0470.v1
Study protocol of the GLOW study: maximising treatment options for recurrent glioblastoma patients by whole genome sequencing-based diagnostics—a prospective multicenter cohort study
Mark P. Van Opijnen, Marike L. D. Broekman, Filip Y. F. De Vos, Edwin Cuppen, Jacobus J. M. Van Der …
Lost by Transcription: Fork Failures, Elevated Expression, and Clinical Consequences Related to Deletions in Metastatic Colorectal Cancer
Marcel Smid, Saskia M. Wilting, John W. M. Martens International Journal of Molecular Sciences, 2022, DOI: 10.3390/ijms23095080
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma
James T. Topham, Erica S. Tsang, Joanna M. Karasinska, Andrew Metcalfe, Hassan Ali, Steve E. Kalloger, Veronika Csizmok, Laura M. …
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G. Mullighan, …
Impact of molecular tumour board discussion on targeted therapy allocation in advanced prostate cancer
Peter H. J. Slootbeek, Iris S. H. Kloots, Minke Smits, Inge M. Van Oort, Winald R. Gerritsen, Jack A. Schalken, …
High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer
Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Abel Gonzalez-Perez, Mafalda Oliveira, Fara Brasó-Maristany, Nusaibah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, …
Germline determinants of the prostate tumor genome
Kathleen E. Houlahan, Jiapei Yuan, Tommer Schwarz, Julie Livingstone, Natalie S. Fox, Weerachai Jaratlerdsiri, Job Van Riet, Kodi Taraszka, Natalie …
Genome-wide mapping of somatic mutation rates uncovers drivers of cancer
Maxwell A. Sherman, Adam U. Yaari, Oliver Priebe, Felix Dietlein, Po-Ru Loh, Bonnie Berger Nature Biotechnology, 2022, DOI: 10.1038/s41587-022-01353-8
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