Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features
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- Whole genome sequencing
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Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features
Luan Nguyen, Arne Van Hoeck & Edwin Cuppen Nature Communications, 2022, DOI
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Apolipoprotein B mRNA-Editing Catalytic Polypeptide-Like–Induced Protein Changes in Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Throughout Disease Progression
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DBFE: Distribution-based feature extraction from copy number and structural variants in whole-genome data
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Temporal Dissection of Altered Pathways during the Evolution of Cancer
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Trastuzumab and pertuzumab combination therapy for advanced pre-treated HER2 exon 20-mutated non-small cell lung cancer
J.M. Van Berge Henegouwen, M. Jebbink, L.R. Hoes, H. Van Der Wijngaart, L.J. Zeverijn, D.L. Van Der Velden, P. Roepman, …
Het aantal WGS- samples dat Hartwig Medical Foundation heeft, is uniek in het onderzoeksveld en groeit snel. Toen we begonnen waren het er 3.500 en dat zijn er nu al meer dan 5.000.