Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns

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Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns

13-12-2023

Simon Grund Sørensen, Amruta Shrikhande, Gustav Alexander Poulsgaard, Mikkel Hovden Christensen, Johanna Bertl, Britt Elmedal Laursen, Eva R Hoffmann, Jakob …

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Pan-cancer whole-genome comparison of primary and metastatic solid tumours

13-12-2023

Francisco Martínez-Jiménez, Ali Movasati, Sascha Remy Brunner, Luan Nguyen, Peter Priestley, Edwin Cuppen, Arne Van Hoeck Nature, May 10 2023, …

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Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning

13-12-2023

Anouk C. De Jong, Alexandra Danyi, Job Van Riet, Ronald De Wit, Martin Sjöström, Felix Feng, Jeroen De Ridder, Martijn …

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The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy

13-12-2023

Johanne Ahrenfeldt, Ditte S. Christensen, Andreas B. Østergaard, Judit Kisistók, Mateo Sokač, Nicolai J. Birkbak, Albert Rübben PLOS ONE, 2023, …

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Tobacco Smoking-Related Mutational Signatures in Classifying Smoking-Associated and Nonsmoking-Associated NSCLC

13-12-2023

Sophie M. Ernst, Joanne M. Mankor, Job Van Riet, Jan H. Von Der Thüsen, Hendrikus J. Dubbink, Joachim G.J.V. Aerts, …

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Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade

13-12-2023

Mahnoor Mahmood, Eric Minwei Liu, Amy L. Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Alejandro Huerta Uribe, Engy Shokry, Alex L. Young, …

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Using genomic scars to select immunotherapy beneficiaries in advanced non-small cell lung cancer

13-12-2023

H. C. Donker, B. Van Es, M. Tamminga, G. A. Lunter, L. C. L. T. Van Kempen, E. Schuuring, T. …

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Identifying somatic changes in drug transporters using whole genome and transcriptome sequencing data of advanced tumors

10-01-2023

Wesley S. van de Geer, Ron H.J. Mathijssen, Job van Riet, Neeltje Steeghs, Mariette Labots, Carla van Herpen, Lot A. …

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