The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy

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The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy

12-08-2026

Johanne Ahrenfeldt, Ditte S. Christensen, Andreas B. Østergaard, Judit Kisistók, Mateo Sokač, Nicolai J. Birkbak & Albert Rübben PLOS ONE, …

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Identifying somatic changes in drug transporters using whole genome and transcriptome sequencing data of advanced tumors

12-08-2026

Wesley S. Van De Geer, Ron H.J. Mathijssen, Job Van Riet, Neeltje Steeghs, Mariette Labots, Carla Van Herpen, Lot A. …

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Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours

12-08-2026

Birgit S. Geurts, Thomas W. Battaglia, J. Maxime Van Berge Henegouwen, Laurien J. Zeverijn, Gijs F. De Wit, Louisa R. …

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Using genomic scars to select immunotherapy beneficiaries in advanced non-small cell lung cancer

12-08-2026

H. C. Donker, B. Van Es, M. Tamminga, G. A. Lunter, L. C. L. T. Van Kempen, E. Schuuring, T. …

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Heritable defects in telomere and mitotic function selectively predispose to sarcomas

12-08-2026

Mandy L. Ballinger, Swetansu Pattnaik, Piyushkumar A. Mundra, Milita Zaheed, Emma Rath, Peter Priestley, Jonathan Baber, Isabelle Ray-Coquard, Nicholas Isambert, …

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Hotspot propensity across mutational processes

12-08-2026

Claudia Arnedo-Pac, Ferran Muiños, Abel Gonzalez-Perez & Nuria Lopez-Bigas Molecular Systems Biology, 2023, DOI

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The genomic and transcriptomic landscape of advanced renal cell cancer for individualized treatment strategies

12-08-2026

K. De Joode, W. S. Van De Geer, G. J. L. H. Van Leenders, P. Hamberg, H. M. Westgeest, A. …

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Mutational processes of tobacco smoking and APOBEC activity generate protein-truncating mutations in cancer genomes

11-08-2026

Nina Adler, Alexander T. Bahcheli, Kevin C. L. Cheng, Khalid N. Al-Zahrani, Mykhaylo Slobodyanyuk, Diogo Pellegrina, Daniel Schramek & Jüri Reimand …

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Heritable defects in telomere and mitotic function selectively predispose to sarcomas

12-02-2026

Mandy L. Ballinger, Swetansu Pattnaik, Piyushkumar A. Mundra, Milita Zaheed, Emma Rath, Peter Priestley, Jonathan Baber, Isabelle Ray-Coquard, Nicholas Isambert, …

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