Impact of DNA damage repair defects and aggressive variant features on response to carboplatin‐based chemotherapy in metastatic castration‐resistant prostate cancer
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Impact of DNA damage repair defects and aggressive variant features on response to carboplatin‐based chemotherapy in metastatic castration‐resistant prostate cancer
Peter H. J. Slootbeek, Marleen L. Duizer, Maarten J. Van Der Doelen, Iris S. H. Kloots, Malou C. P. Kuppen, …
The evolution of hematopoietic cells under cancer therapy
Oriol Pich, Albert Cortes-Bullich, Ferran Muiños, Marta Pratcorona, Abel Gonzalez-Perez & Nuria Lopez-Bigas Nature Communications, 2021, DOI
Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer
Andrew Woolston, Louise J. Barber, Beatrice Griffiths, Oriol Pich, Nuria Lopez-Bigas, Nik Matthews, Sheela Rao, David Watkins, Ian Chau, Naureen …
A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer
Sander A. L. Palit, Jeroen Van Dorp, Daniel Vis, Cor Lieftink, Simon Linder, Roderick Beijersbergen, Andries M. Bergman, Wilbert Zwart …
Evaluation of the Khorana, PROTECHT, and 5‐SNP scores for prediction of venous thromboembolism in patients with cancer
Noori A.M. Guman, Roos J. Van Geffen, Frits I. Mulder, Thijs F. Van Haaps, Vahram Hovsepjan, Mariette Labots, Geert A. …
In silico saturation mutagenesis of cancer genes
Ferran Muiños, Francisco Martínez-Jiménez, Oriol Pich, Abel Gonzalez-Perez & Nuria Lopez-Bigas Nature, 2021, DOI
Learning mutational signatures and their multidimensional genomic properties with TensorSignatures
Harald Vöhringer, Arne Van Hoeck, Edwin Cuppen & Moritz Gerstung Nature Communications, 2021, DOI
Network-Based Analysis to Identify Drivers of Metastatic Prostate Cancer Using GoNetic
Louise De Schaetzen Van Brienen, Giles Miclotte, Maarten Larmuseau, Jimmy Van Den Eynden & Kathleen Marchal Cancers, 2021, DOI
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